Upper GI - British Journal of Surgery

Emergency surgery

Scientific Surgery

A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

Authors: O’Leary DP, Walsh SM, Bolger J, Baban C, Humphreys H, O’Grady S et al.

Scientific Surgery

Effect of oral moxifloxacin vs intravenous ertapenem plus oral levofloxacin for treatment of uncomplicated acute appendicitis. The APPAC II randomized clinical trial. JAMA 2021; 325: 353-362.

Authors: Sipppola S, Haijanen J, Gronooos J, Rautio T, Nordstrom P, Rantanen T et al.

Scientific Surgery

A randomized trial comparing antibiotics with appendectomy for appendicitis. N Engl J Med 2020; 383: 1907-1919.

Authors: The CODA Collaborative

Scientific Surgery

Quality of life and patient satisfaction at 7-year follow-up of antibiotic therapy vs appendectomy for uncomplicated acute appendicitis. A secondary analysis of a randomized clinical trial. JAMA Surg 2020; 155: 283-289.

Authors: Sippola S, Haijanen J, Viinikainen L, Gronroos J, Paajanen H, Rautio T et al.

Scientific Surgery

Are postoperative intravenous antibiotics indicated after laparoscopic appendicectomy for simple appendicitis? A prospective double-blinded randomized controlled trial. Ann Surg 2020; 272: 248-252.

Authors: Mennie N, Panabokke G, Chang A, Tanny ST, Cheng W, Pacilli M et al.

Scientific Surgery

Non-operative treatment versus appendectomy for acute non-perforated appendicitis in children: five-year follow up of a randomized controlled pilot trial. Ann Surg 2020; 271: 1030-1035.

Authors: Patkova B, Svenningsson A, Almström M, Eaton S, Wester T, Svensson JF et al.

Scientific Surgery

Povidone-iodine irrigation for pediatric perforated appendicitis may be protective. A Bayesian pilot randomized controlled trial. Ann Surg 2020; 271: 827-833

Authors: Anderson KT, Putnam LR, Bartz-Kurycki MA, Hamilton EC, Yafi M, Pedroza C et al.

Scientific Surgery

Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children. A systematic review and meta-analysis. Ann Surg 2019; 270: 1028-1040

Authors: Podda M, Gerardi C, Cillara N, Fearnhead N, Gomes CA, Birindelli A et al.

Scientific Surgery

Risk of appendiceal neoplasm in periappendicular abscess in patients treated with interval appendectomy vs follow-up with magnetic resonance imaging. 1-year outcomes of the Peri–appendicitis Acuta randomized clinical trial. JAMA Surg 2019; 154: 200-207.

Authors: Mällinen J, Rautio T, Grönroos J, Rantanen T, Nordström P, Savolainen H et al.

Scientific Surgery

Five-year follow-up of antibiotic therapy for uncomplicated acute appendicitis in the APPAC randomized clinical trial. JAMA 2018; 320: 1259-1265.

Authors: Salminen P, Hannu Paajanen T, Rautio T, Nordström P, Aarnio M, Rantanen T et al.

Scientific Surgery

Comparison of superficial surgical site infection between delayed primary versus primary wound closure in complicated appendicitis: a randomized controlled trial. Ann Surg 2018; 267: 631-637.

Authors: Siribumrungwong B, Chantip A, Noorit P, Wilasrusmee C, Ungpinitpong W, Chotiya P et al.

Scientific Surgery

Optimal stump management in laparoscopic appendectomy: a network meta-analysis by the Minimally Invasive Surgery Synthesis of Interventions and Outcomes Network. Surgery 2017: 162: 994-1005.

Authors: Antoniou SA, Mavridis D, Hajibandeh S, Antoniou GA, Gorter R, Tenhagen M et al.

Scientific Surgery

Antibiotics versus surgical therapy for uncomplicated appendicitis: systematic review and meta-analysis of controlled trials (PROSPERO 2015: CRD42015016882). Ann Surg 2017; 265: 889-900.

Authors: Harnoss J, Zelienka I, Probst P, Grummich K, Müller-Lantzsch C, Harnoss J et al.

Scientific Surgery

Antibiotics versus appendicectomy for the treatment of uncomplicated acute appendicitis: an updated meta-analysis of randomised controlled trials. World J Surg 2016; 40: 2305–2318.

Authors: Rollins K, Varadhan KK, Neal KR, Lobo DN

Scientific Surgery

A prospective randomized controlled trial of laparoscopic repair versus open repair for perforated peptic ulcers. Surgery 2016; 159: 451–458.

Authors: Ge B, Wu M, Chen Q, Chen Q, Lin R, Liu L et al.