Upper GI - British Journal of Surgery

Scientific Surgery

Morbidity and mortality of patients who underwent minimally invasive esophagectomy after neoadjuvant chemo-radiotherapy vs neoadjuvant chemotherapy for locally advanced esophageal squamous cell carcinoma. A randomized clinical trial. JAMA Surg 2021; 156: 444-451.

Authors: Wang H, Tang H, Fang Y, Tan L, Yin J, Shen Y et al.

Scientific Surgery

A randomized clinical trial evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis. Results of the COMMA Trial. Ann Surg 2021; 274: 240-247.

Authors: O’Leary DP, Walsh SM, Bolger J, Baban C, Humphreys H, O’Grady S et al.

Scientific Surgery

Five-year survival outcomes of hybrid minimally invasive esophagectomy in esophageal cancer. Results of the MIRO Randomized Clinical Trial. JAMA Surg 2021; 156: 323-332.

Authors: Nuytens F, Dabakuyo-Yonli TS, Meunier B, Gagnière J, Collet D, D’Journo XB et al.

Scientific Surgery

Palliative radiotherapy after oesophageal cancer stenting (ROCS): a multicentre, open-label, phase 3 randomised controlled trial. Lancet Gastroenterol Hepatol 2021; 6: 292-303.

Authors: Adamson DA, Byrne A, Porter C, Blazeby J, Griffiths G, Nelson A et al.

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Snapshot quiz (August 2021 [2])

A 34-year-old woman presented with a 20 cm intra-abdominal tumour with large draining veins and shunting surrounding the mass, detected by abdominal computed tomography (CT) scan. Six years before she underwent surgery for a pelvic tumour. What is the diagnosis?

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Snapshot quiz (August 2021 [1])

An 8 year old boy presented with colicky abdominal pain and chronic anemia. Faecal occult blood analysis was positive, upper and lower GI endoscopy were unremarkable. 99mTC labeled RBC scan showed an abnormal accumulation of tracer in the distal small bowel on the right side of abdomen. Diagnostic laparoscopy followed by open resection was done. What is the diagnosis?

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Scientific Surgery

Effect of laparoscopic sleeve gastrectomy vs Roux-en-Y gastric bypass on weight loss and quality of life at 7 Years in patients with morbid obesity. The SLEEVEPASS randomized clinical trial. JAMA Surg 2021; 156: 137-146.

Authors: Gronroos S, Helmio M, Juuti A, Tiusanen R, Hurme S, Loyttyniemi E et al.

Scientific Surgery

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial. Lancet Gastro Hepatol 2021; 6: 120-127.

Authors: Kono K, Misawa K, Yabusaki H, Kinoshita T, Lau PC, Kim YW et al.

Scientific Surgery

Assessment of robotic versus laparoscopic distal gastrectomy for gastric cancer. A randomized controlled trial. Ann Surg 2021; 273: 858-867.

Authors: Lu J, Zheng C-H, Xu B-B, Xie J-W, Wang J-B, Lin J-X et al.

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Snapshot quiz (June 2021 [1])

A 75-year-old man with a history of diverticulosis and open appendicectomy presented with intermittent abdominal pain, nausea and vomiting, constipation, reduced appetite and weight loss of 5 kg during the last month. The patient underwent an exploratory laparotomy (Figures a and b). What is the diagnosis?

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Scientific Surgery

Adjuvant nivolumab in resected esophageal or gastroesophageal junction cancer. N Engl J Med 2021; 384: 1191-1203.

Authors: Kelly RJ, Ajani JA, Kuzdzal J, Zander T, van Cutsem E, Piessen G et al.

Scientific Surgery

Laparoscopic ileocaecal resection versus infliximab for terminal ileitis in Crohn’s disease: retrospective long-term follow-up of the LIR!C trial. Lancet Gastroenterol Hepatol 2020; 5: 900-907.

Authors: Stevens TW, Haasnoot GR, Buskens CJ, de Groof EJ, Eshuis EJ, Gardenbroek TJ et al.

Scientific Surgery

Effect of oral moxifloxacin vs intravenous ertapenem plus oral levofloxacin for treatment of uncomplicated acute appendicitis. The APPAC II randomized clinical trial. JAMA 2021; 325: 353-362.

Authors: Sipppola S, Haijanen J, Gronooos J, Rautio T, Nordstrom P, Rantanen T et al.

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Snapshot quiz (April 2021 [2])

At emergency laparotomy, a 27-year-old man was found to have a localized perforation of the ascending colon with a surrounding abscess. There were multiple other abnormal areas in the small bowel. What is the diagnosis?

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Scientific Surgery

Effect of gastric bypass vs best medical treatment on early-stage chronic kidney disease in patients with type 2 diabetes and obesity. A randomized clinical trial. JAMA Surg 2020; 155: e200420.

Authors: Cohen RV, Pereira TV, Aboud CM, Petry TBZ, Correa JLL, Schiavon CA et al.

Scientific Surgery

Efficacy and safety of ursodeoxycholic acid for the prevention of gallstone formation after gastrectomy in patients with gastric cancer. The PEGASUS-D randomized clinical trial. JAMA Surg 2020; 155: 703-711.

Authors: Lee SH, Jang DK, Yoo M-W, Hwang S-H, Ryu S-Y, Kwon OK et al.

Scientific Surgery

Laparoscopic sleeve gastrectomy versus laparoscopic Roux-en-Y gastric bypass. A systematic review and meta-analysis of weight loss, comorbidities, and biochemical outcomes from randomized controlled trials. Ann Surg 2021; 273: 66-74.

Authors: Lee Y, Doumouras A, Yu J, Aditya I, Gmora S, Anvari M et al.

Scientific Surgery

Banded versus nonbanded sleeve gastrectomy. A randomized controlled trial with 3 years of follow-up. Ann Surg 2020; 272: 690-695.

Authors: Fink J, Hetzenecker A, Seifert G, Runkel M, Laessle C, Fichtner-Feigl S et al.

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