This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Resection of cavity shave margins in stage 0–III breast cancer patients undergoing breast conserving surgery. A prospective multicenter randomized controlled trial. Ann Surg 2021; 273: 876-881.

Published: 1st November 2021

Authors: Dupont E, Tsangaris T, Garcia-Cantu C, Howard-McNatt M, Chiba A, Berger AC et al.

Conclusion

In this study that included 396 procedures, women randomized to cavity shave were significantly less likely to have positive margins (9.7 versus 36 per cent, P<0.001) and to require re-excision or mastectomy (8.7 versus 33.5 per cent, P<0.001).

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