This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Randomized phase III trial exploring the use of long-acting release octreotide in the prevention of chemotherapy-induced diarrhea in patients with colorectal cancer : The LARCID Trial. J Clin Oncol 2014; 32: 1006-1011.
Published: 26th August 2014
Authors: Hoff PM, Saragiotto DF, Barrios H, del Giglio A, Coutinho AK, Andrade AC et al. et al.
Conclusion
Long-acting octreotide (30mg IM injection every four weeks) did not reduce the rate of diarrhoea (76.1 versus 78.9 per cent in controls) in this study that included 130 patients.
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