This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Oncological benefits of neoadjuvant chemoradiation with gemcitabine versus upfront surgery in patients with borderline resectable pancreatic cancer: a prospective, randomized, open-label, multicenter phase 2/3 trial. Ann Surg 2018; 268: 215-222.
Published: 15th October 2018
Authors: Jang J-Y, Han Y, Lee H, Kim S-W, Kwon W, Lee K-H et al.
Conclusion
Fifty patients were included. Neoadjuvant chemotherapy significantly improved median two year survival: 40.7 versus 26.1 per cent, P=0.028. It also improved the R0 resection rate: 51.8 versus 26.1 per cent, P=0.004.
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