This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Effect of more vs less frequent follow-up testing on overall and colorectal cancer–specific mortality in patients with stage II or III colorectal cancer. The COLOFOL Randomized Clinical Trial. JAMA 2018; 319: 2095-2103.
Published: 9th August 2018
Authors: Wille-Jørgensen P, Syke I, Smedh K, Laurberg S, Nielsen DT, Petersen SH et al.
Conclusion
Compared to low-frequency follow-up, high-frequency follow-up did not improve outcomes in this trial that included 2509 patients. The 5-year cancer-specific mortality rate risk difference was 0.8 per cent, 95 per cent confidence interval -1.7 to 3.3 per cent; P=0.5.
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