The international surgical journal with global reach

This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Combined surgery and extensive intraoperative peritoneal lavage vs surgery alone for treatment of locally advanced gastric cancer. The SEIPLUS randomized clinical trial. JAMA Surg 2019; 154: 610-616

Published: 23rd December 2019

Authors: Guo J, Xu A, Sun X, Zhao X, Xia Y, Rao H et al.

Conclusion

Some 550 patients having gastrectomy for gastric cancer were included. The addition of extensive intraoperative lavage reduced the mortality rate (none versus 1.9 per cent, P=0.02) and perioperative complication rates (11.1 versus 17 per cent, P=0.04).

Pubmed Link

You may also be interested in

Scientific Surgery

Five-year survival outcomes of hybrid minimally invasive esophagectomy in esophageal cancer. Results of the MIRO Randomized Clinical Trial. JAMA Surg 2021; 156: 323-332.

Authors: Nuytens F, Dabakuyo-Yonli TS, Meunier B, Gagnière J, Collet D, D’Journo XB et al.

Scientific Surgery

Randomized comparison of gastric tube reconstruction with and without duodenal diversion plus Roux-en-Y anastomosis after esophagectomy. Ann Surg 2020; 272: 48-54.

Authors: Yano M, Sugimura K, Miyata H, Motoori M, Tanaka K, Omori T et al.

Scientific Surgery

Health-related quality of life following hybrid minimally invasive versus open esophagectomy for patients with esophageal cancer. Analysis of a multicenter, open-label, randomized phase III controlled trial. The MIRO Trial. Ann Surg 2020; 271: 1023-1029.

Authors: Mariette C, Markar S, Dabakuyo-Yonli TS, Meunier B, Pezet D, Collet D et al.

Scientific Surgery

Survival outcomes after laparoscopy-assisted distal gastrectomy versus open gastrectomy with nodal dissection for clinical stage 1A or 1B gastric cancer (JCOG0912): a multicenter, non-inferiority, phase 3 randomised controlled trial. Lancet Gastroenterol Hepatol 2020; 5: 142-151

Authors: Katai H, Mizusawa J, Katayama H, Morita S, Yamada T, Brando E et al.

Scientific Surgery

Direct oral feeding following minimally invasive esophagectomy (NUTRIENT II trial). An international, multicenter, open-label randomized controlled trial. Ann Surg 2020; 271: 41-47

Authors: Berkelmans GH, Fransen LFC, Dolmans-Zwartjes ACP, Kouwenhoven EA, van Det MJ, Nilsson M et al.

Scientific Surgery

Short-term outcomes of a multicenter randomized controlled trial comparing laparoscopic distal gastrectomy with D2 lymphadenectomy to open distal gastrectomy for locally advanced gastric cancer (KLASS-02-RCT). Ann Surg 20129; 270: 983-991

Authors: Lee H-J, Hyung WJ, Yang H-K, Han S, Park Y-K, An JY et al.

Scientific Surgery

Robot-assisted minimally invasive thoracolaparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer. A randomized controlled trial. Ann Surg 2019; 269: 621-630.

Authors: van der Sluis PC, van der Horst S, May AM, Schippers C, Brosens L, Joore HC et al.

Scientific Surgery

Hybrid minimally invasive esophagectomy for esophageal cancer. N Engl J Med 2019; 380: 152-162.

Authors: Mariette C, Markar SR, Dabakuyo-Yonli TS, Meunier B, Pezet D, Collet D et al.

Scientific Surgery

Early oral feeding following McKeown minimally invasive esophagectomy: an open-label, randomized, controlled, noninferiority trial. Ann Surg 2018; 267: 435-442.

Authors: Sun H-B, Li Y, Liu X-B, Zhang R-X, Wang Z-F, Lerut T et al.

Scientific Surgery

Circular stapling versus triangulating stapling for the cervical esophagogastric anastomosis after esophagectomy in patients with thoracic esophageal cancer: A prospective, randomized, controlled trial. Surgery 2017; 162: 131-138.

Authors: Hayata K, Nakamori M, Nakamura M, Ojima T, Iwahashi M, Katsuda M et al.

Scientific Surgery

Minimally invasive versus open esophageal resection: three-year follow-up of the previously reported randomized controlled trial: The TIME Trial. Ann Surg 2017; 266: 232-236.

Authors: Straatman J, van der Wielen N, Cuesta MA, Daams F, Roig Garcia J, Bonavina L et al.

Scientific Surgery

A randomized controlled trial comparing antioxidant-enriched enteral nutrition with immune-enhancing enteral nutrition after esophagectomy for cancer. Surg Today 2013; 43:  1240-1249.

Authors: Nagano T, Fujita H, Tanaka T, Matono S, Murata K, Ishibashi N et al. et al.