This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Adjuvant nivolumab versus ipilimumab in resected stage III or IV melanoma. N Engl J Med 2017; 377: 1824-1835.
Published: 25th January 2018
Authors: Weber J, Mandala M, Del Vecchio M, Gogas HJ, Arance AM, Cowey CL et al.
Conclusion
In this trial that included 906 patients, the active agents were given intravenously for up to one year. Twelve month recurrence-free survival was 70.5 per cent with nivolumab and 60.8 per cent with ipilimumab, P<0.001. Side effects were more common with ipilimumab (45.9 versus 14.4 per cent).
Pubmed LinkYou may also be interested in
Scientific Surgery
Authors: Dummer R, Hauschild A, Santinami M, Atkinson V, Mandala M, Kirkwood JM et al.
Scientific Surgery
Authors: Zimmer S, Livingstone E, Hassel JC, Fluck M, Eigentler T, Loquai C et al.
Scientific Surgery
Authors: Utjes D, Malmstedt J, Teras J, Drzewiecki K, Gullestad HP, Ingvar C et al.
Scientific Surgery
Authors: Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson V, Dalle S et al.
Scientific Surgery
Authors: Long GV, Hauschild A, Santinami M, Atkinson V, Mandalà M, Chiarion-Sileni V et al.
Scientific Surgery
Authors: Faries MB, Thompson JF, Cochran AJ, Andtbacka RH, Mozzillo N, Zager JS et al.
Scientific Surgery
Authors: Faries MB, Thompson JF, Cochran AJ, Andtbacka RH, Mozzillo N, Zager JS et al.
Scientific Surgery
Authors: Agarwala SS, Lee SJ, Yip W, Rao UN, Tarhini AA, Cohen GI et al.
Scientific Surgery
Authors: Eggermont AMM, Chiarion-Sileni V, Grob J-J, Dummer R, Wolchok JD, Schmidt H et al.
Scientific Surgery
Authors: McMasters KM, Egger ME, Edwards MJ, Ross MI, Reintgen DS, Noyes RD et al.