This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
The evolving role of gene‐based treatment in surgery. BJS 2005; 92: 1466-1480.
Published: 4th November 2005
Authors: P. H. Tan, C. L. H. Chan, C. Chan, A. J. T. George
Background
The completion of the sequencing of the human genome in 2003 marked the dawn of a new era of human biology and medicine. Although these remarkable scientific advances improve the understanding of human biology, the question remains how this rapidly expanding knowledge of functional genomics affects the role of surgeons. This article reviews the potential therapeutic application of gene therapy for various surgical conditions.
Method
The core of this review was derived from a Medline database literature search.