This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Systematic review of surgical treatment of subclinical Cushing’s syndrome. BJS 2015; 102: 318-330.
Published: 2nd February 2015
Authors: M. Iacobone, M. Citton, M. Scarpa, G. Viel, M. Boscaro, D. Nitti et al.
Background
Subclinical Cushing's syndrome (
Method
A systematic review was performed.
Results
Of the 105 papers screened, seven were selected; there were six retrospective studies and one randomized clinical trial, including 230 patients. Data analysis was limited by heterogeneity in definition of
Conclusion
Laparoscopic adrenalectomy seems to be beneficial in reversing several metabolic effects of hypercortisolism, with a low morbidity rate. However, the heterogeneity and low quality of the available studies preclude definitive recommendations.
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