This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS

Systematic review and meta‐analysis of oesophageal Doppler‐guided fluid management in colorectal surgery. BJS 2013; 100: 1701-1708.

Published: 14th November 2013

Authors: S. Srinivasa, D. P. Lemanu, P. P. Singh, M. H. G. Taylor, A. G. Hill

Background

Oesophageal Doppler monitor (ODM)‐guided fluid therapy has been recommended for routine use in patients undergoing colorectal surgery. However, recent trials have suggested either equivalent or inferior results for patients randomized to ODM‐guided fluid management, especially when compared with fluid restriction or within the context of optimized perioperative care. Hence, an updated systematic review and meta‐analysis was conducted.

Method

A systematic review and meta‐analysis was conducted of all randomized trials exploring ODM‐guided fluid management in major colorectal surgery with the endpoints total complications and length of hospital stay (LOS). Subset analyses were planned a priori specifically to investigate the role of the ODM in the context of fluid restriction or optimized perioperative care.

Results

Six high‐quality trials comprising a total of 691 patients were included in the final analysis. ODM‐guided fluid therapy did not influence the incidence of complications (odds ratio 0·74, 95 per cent confidence interval (c.i.) 0·50 to 1·11; P = 0·15), with moderate heterogeneity in the results (I² = 33 per cent; P = 0·19). There was no difference in mean LOS between patients receiving ODM‐guided fluid therapy and controls: mean difference −0·88 (95 per cent c.i. –2·89 to 1·13) days (P = 0·39). There was no difference in complications or LOS when ODM‐guided fluid therapy was compared with fluid restriction or used within an otherwise optimized perioperative environment.

Conclusion

ODM‐guided fluid therapy did not influence LOS or complications in patients undergoing colorectal surgery. Results favouring the ODM were seen only in early studies, whereas newer trials did not show any benefit from such monitoring.

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