This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Retrospective analysis of type of hepatic resection for hepatocellular carcinoma. BJS 2000; 87: 65-70.
Published: 10th December 2002
Authors: S. Takano, H. Oishi, S. Kono, S. Kawakami, M. Nakamura, N. Kubota et al.
Background
Hepatic resection for hepatocellular carcinoma is now considered a relatively safe procedure, owing to refined surgical techniques and management.
Method
Three hundred different types of hepatic resection performed in one hospital were reviewed retrospectively. The operative morbidity and mortality rates and long‐term survival were assessed.
Results
Tumours were extirpated by lobectomy or extended lobectomy in 48 patients, by segmentectomy in 53, by subsegmentectomy in 94 and by partial resection in 105. The overall hospital mortality rate was 4 per cent (13 of 300). No operative death occurred after lobectomy or extended lobectomy. Segmentectomy and subsegmentectomy were associated with high postoperative complication and hospital mortality rates. There was a significant difference in survival rate between patients with and without a cancer‐free surgical margin of more than 1·0 cm. The overall 5‐ and 9‐year survival rates were 51 and 9 per cent respectively. Rates were 56 and 24 per cent for lobectomy or extended lobectomy.
Conclusion
For tumours of 2·1 cm or more in size lobectomy appears to carry the least risk of postoperative complications and death in hospital and best achieves a cancer‐free surgical margin. © 2000 British Journal of Surgery Society Ltd
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