This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Randomized clinical trial of the effect of perioperative synbiotics versus no synbiotics on bacterial translocation after oesophagectomy. BJS 2014; 101: 189-199.
Published: 9th January 2014
Authors: Y. Yokoyama, E. Nishigaki, T. Abe, M. Fukaya, T. Asahara, K. Nomoto et al.
Background
The impact of perioperative synbiotics on bacterial translocation and subsequent bacteraemia after oesophagectomy is unclear. This study investigated the effect of perioperative synbiotic administration on the incidence of bacterial translocation to mesenteric lymph nodes (
Method
Patients with oesophageal cancer were randomized to receive perioperative synbiotics or no synbiotics (control group).
Results
Some 42 patients were included. There was a significant difference between the two groups in detection levels of microorganisms in the
Conclusion
Perioperative use of synbiotics reduces the incidence of bacteria in the
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