This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Prognostic impact of extracapsular lymph node involvement after neoadjuvant therapy and oesophagectomy. BJS 2016; 103: 1658-1664.
Published: 3rd October 2016
Authors: S. M. Lagarde, M. Navidi, S. S. Gisbertz, H. W. M. van Laarhoven, K. Sumpter, S. L. Meijer et al.
Background
The significance of extracapsular lymph node involvement (
Method
Data from a consecutive series of patients treated at two European centres were analysed. All patients with squamous cell carcinoma or adenocarcinoma of the oesophagus or gastro‐oesophageal junction, who received neoadjuvant chemotherapy or chemoradiation followed by transthoracic oesophagectomy and two‐field lymphadenectomy with curative intent, were included.
Results
Between January 2000 and September 2013, 704 patients underwent oesophagectomy after neoadjuvant therapy. A median of 28 (range 5–77) nodes per patient was recovered. Some 347 patients (49·3 per cent) had no
Conclusion
The presence of extracapsular
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