This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Patterns of disease relapse in primary extremity soft‐tissue sarcoma. BJS 2016; 103: 1487-1496.
Published: 9th August 2016
Authors: H. G. Smith, N. Memos, J. M. Thomas, M. J. F. Smith, D. C. Strauss, A. J. Hayes et al.
Background
Extremity soft‐tissue sarcomas comprise a range of distinct histological subtypes. This study aimed to characterize the patterns of disease relapse in patients undergoing resection of primary extremity soft‐tissue sarcoma.
Method
All patients who had resection of primary extremity soft‐tissue sarcoma at the Royal Marsden Hospital between January 2004 and January 2014 were identified from an institutional database.
Results
In the period examined, 556 patients underwent resection. The most common histological subtypes were undifferentiated pleomorphic sarcoma (169 patients, 30·4 per cent), well differentiated liposarcoma (63, 11·3 per cent), myxoid liposarcoma (62, 11·2 per cent), myxofibrosarcoma (54, 9·7 per cent) and leiomyosarcoma (39, 7·0 per cent). Local recurrence‐free survival (
Conclusion
Although histological subtype was not found to be an independent prognostic factor for oncological outcomes, the site of first metastasis differed significantly between subtypes.
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