This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Network meta‐analysis of protocol‐driven care and laparoscopic surgery for colorectal cancer. BJS 2016; 103: 1783-1794.
Published: 20th October 2016
Authors: A. C. Currie, G. Malietzis, J. T. Jenkins, T. Yamada, H. Ashrafian, T. Athanasiou et al.
Background
Laparoscopic approaches and standardized recovery protocols have reduced morbidity following colorectal cancer surgery. As the optimal regimen remains inconclusive, a network meta‐analysis was undertaken of treatments for the development of postoperative complications and mortality.
Method
Results
Forty trials reporting on 11 516 randomized patients were included with the network. Open surgery within conventional perioperative care was the index for comparison. The
Conclusion
Laparoscopic surgery combined with protocol‐driven care reduces colorectal cancer surgery complications, but not mortality. The reduction in complications with protocol‐driven care is greater for open surgery than for laparoscopic approaches. Registration number:
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