This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Mortality from trauma haemorrhage and opportunities for improvement in transfusion practice. BJS 2016; 103: 357-365.
Published: 3rd February 2016
Authors: S. J. Stanworth, R. Davenport, N. Curry, F. Seeney, S. Eaglestone, A. Edwards et al.
Background
The aim of this study was to describe the prevalence, patterns of blood use and outcomes of major haemorrhage in trauma.
Method
This was a prospective observational study from 22 hospitals in the
Results
A total of 442 patients were identified during a median enrolment interval of 20 (range 7–24) months. Based on this, the national incidence of trauma haemorrhage was estimated to be 83 per million. The median age of patients in the study cohort was 38 years and 73·8 per cent were men. The incidence of major haemorrhage increased markedly in patients aged over 65 years. Thirty‐six deaths within 24 h of admission occurred within the first 3 h. At 24 h, 79 patients (17·9 per cent) had died, but mortality continued to rise even after discharge. Patients who received a cumulative ratio of fresh frozen plasma to
Conclusion
There is a high burden of trauma haemorrhage that affects all age groups. Research is required to understand the reasons for death after the first 24 h and barriers to timely transfusion support.
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