This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Meta‐analysis of antibiotics for simple hand injuries requiring surgery. BJS 2016; 103: 487-492.
Published: 29th February 2016
Authors: G. R. F. Murphy, M. D. Gardiner, G. E. Glass, I. A. Kreis, A. Jain, S. Hettiaratchy et al.
Background
Simple hand trauma is very common, accounting for 1·8 million emergency department visits annually in the
Method
Embase,
Results
Thirteen studies (2578 patients) were included, comprising five double‐blind randomized clinical trials, five prospective trials and three cohort studies. There was no significant difference in infection rate between the antibiotic and placebo/no antibiotic groups (
Conclusion
There was moderate‐quality evidence that routine use of antibiotics does not reduce the infection rate in simple hand wounds that require surgery.
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