This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Long‐term results of abdominal salvage surgery following restorative proctocolectomy. BJS 2006; 93: 231-237.
Published: 23rd January 2006
Authors: P. P. Tekkis, A. G. Heriot, J. J. Smith, P. Das, A. Canero, R. J. Nicholls et al.
Background
This study evaluated outcomes of patients who underwent abdominal salvage ileal pouch redo surgery and identified factors associated with pouch failure following restorative proctocolectomy.
Method
Data on patients who underwent abdominal salvage surgery in a tertiary referral centre between 1985 and 2003 were collected. Outcomes studied included failure of salvage and bowel function of patients with an intact intestine.
Results
One hundred and twelve patients underwent 117 pouch salvage procedures for ulcerative colitis (86), indeterminate colitis/ulcerative colitis (eight), indeterminate colitis/Crohn's disease (three), familial adenomatous polyposis (ten) and other conditions (five). The most common indications for pouch salvage were intra‐abdominal sepsis (45 patients), anastomotic stricture (13) and retained rectal stump (35). Median follow‐up was 46 (range 1–147) months. Twenty‐four patients (21·4 per cent) experienced pouch failure, the incidence of which increased with time. The pouch failed in all patients with Crohn's disease. Successful salvage at 5 years was significantly associated with non‐septic (85 per cent) rather than septic (61 per cent) indications (P = 0·016). Frequency of night‐time defaecation and faecal urgency improved after salvage surgery (P = 0·036 and P = 0·016 respectively at 5‐year follow‐up; n = 32).
Conclusion
Abdominal salvage surgery was associated with a failure rate of 21·4 per cent. A successful outcome was less likely when the procedure was carried out for septic compared with non‐septic indications. The rate of pouch failure increased with length of follow‐up. Copyright © 2006 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
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