This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Impact of postoperative non‐steroidal anti‐inflammatory drugs on adverse events after gastrointestinal surgery. BJS 2014; 101: 1413-1423.
Published: 4th August 2014
Authors: S. J. Chapman, J. Glasbey, M. Kelly, C. Khatri, D. Nepogodiev, J. E. F. Fitzgerald et al.
Background
Recent evidence has suggested an association between postoperative non‐steroidal anti‐inflammatory drugs (
Method
This multicentre study was carried out during a 2‐week interval in September–October 2013. Consecutive adults undergoing elective or emergency gastrointestinal resection were included. The study was powered to detect a 10 per cent increase in major complications (grade III–V according to the Dindo–Clavien classification). The effect of administration of
Results
Across 109 centres, early postoperative
Conclusion
Early use of
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