This is the Scientific Surgery Archive, which contains all randomized clinical trials in surgery that have been identified by searching the top 50 English language medical journal issues since January 1998. Compiled by Jonothan J. Earnshaw, former Editor-in-Chief, BJS
Growth factors in the treatment of diabetic foot ulcers. BJS 2003; 90: 133-146.
Published: 7th January 2003
Authors: S. P. Bennett, G. D. Griffiths, A. M. Schor, G. P. Leese, S. L. Schor
Background
Chronic foot ulceration is a major source of morbidity in diabetic patients. Despite traditional comprehensive wound management, including vascular reconstruction, there remains a cohort of patients with non‐responding wounds, often resulting in amputation. These wounds may benefit from molecular manipulation of growth factors to enhance the microcirculation.
Method
A review of the current literature was performed using Pubmed, with secondary references obtained from key articles.